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ROUTE DEVELOPMENT, ANTIVIRAL STUDIES, FIELD EVALUATION AND TOXICITY OF AN ANTIVIRAL PLANT PROTECTANT

Frontiers of Agricultural Science and Engineering 2022, Volume 9, Issue 1, doi: 10.15302/J-FASE- 2021390

Abstract: identification of NK0238 as a highly effective agent for the prevention and control of diseases caused by plantNK0238 exhibited useful antiviral activities against a variety of viruses both in greenhouse and field

Keywords： antiviral plant protectant / antiviral in the greenhouse / field evaluation / l-trp-NCA / synthesis optimization

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ROUTE DEVELOPMENT, ANTIVIRAL STUDIES, FIELD EVALUATION AND TOXICITY OF AN ANTIVIRAL PLANT PROTECTANT

Wentao XU, Hao TIAN, Hongjian SONG, Yuxiu LIU, Yongqiang LI, Qingmin WANG

Frontiers of Agricultural Science and Engineering Pages 110-119 doi: 10.15302/J-FASE-2021390

Keywords： antiviral plant protectant antiviral in the greenhouse field evaluation L-trp-NCA synthesis optimization

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BIOINSECTICIDES AS FUTURE MAINSTREAM PEST CONTROL AGENTS: OPPORTUNITIES AND CHALLENGES

Frontiers of Agricultural Science and Engineering 2022, Volume 9, Issue 1, Pages 82-97 doi: 10.15302/J-FASE-2021404

Abstract: progress on bioinsecticides which are categorized as biochemical insecticides and their derivatives, plant-incorporated

Keywords： biochemical insecticide / bioinsecticide / microbial bioinsecticides / plant-incorporated protectant

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Direct acting antiviral-induced dynamic reduction of serum

Tung Huynh, Ke-Qin Hu

Frontiers of Medicine 2019, Volume 13, Issue 6, Pages 658-666 doi: 10.1007/s11684-019-0707-7

Abstract: Direct acting antiviral (DAA) treatments may reduce the elevated α fetoprotein (AFP), but data on how

Keywords： chronic hepatitis C α fetoprotein direct acting antiviral treatment cirrhosis

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Design, synthesis, and antiviral properties of 2-aryl-1H-benzimidazole-4-carboxamide derivatives

Xianjin LUO, Zhonglü ZHANG, Yutian YANG, Fei XUE, Naiyun XIU, Yuanbin SHE

Frontiers of Chemical Science and Engineering 2009, Volume 3, Issue 3, Pages 305-309 doi: 10.1007/s11705-009-0021-z

Abstract: Their potent antiviral properties indicated the prospect of new drugs.

Keywords： benzimidazole coxsackie virus B₃ antiviral properties

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Critical roles of chemokines and cytokines in antiviral innate immune responses during rabies virus infection

Ying HUANG, Clement Wesley GNANADURAI, Zhenfang FU

Frontiers of Agricultural Science and Engineering 2017, Volume 4, Issue 3, Pages 260-267 doi: 10.15302/J-FASE-2016116

Abstract: The innate immune response is the first line of defense against viral invasion and pro-inflammatory chemokines and cytokines have a critical function in the innate immune responses against virus infections. The ability of a rabies virus (RABV) to induce the expression of chemokines and cytokines can lead to viral clearance from the central nervous system (CNS), whereas the ability to evade such expression and activation contributes to virulence and pathogenicity. In this review, the crucial contribution of chemokines/cytokines to clearing RABV from the CNS is discussed, including recruiting leukocytes into the CNS, enhancement of blood brain barrier permeability and activation of various immune cells that are essential for viral clearance. In addition, recombinant RABV expressing cytokines and chemokines can induce elevated innate and adaptive immune responses which result in clearing an established wild-type RABV infection in the CNS.

Keywords： antiviral blood brain barrier chemokines and cytokines innate immunity rabies virus

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ANTIVIRAL EFFECTS OF BACTERIOCIN AGAINST ANIMAL-TO-HUMAN TRANSMITTABLE MUTATED SARS-COV-2: A SYSTEMATIC

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 4, Pages 603-622 doi: 10.15302/J-FASE -2021397

Abstract: Despite possessing antiviral traits the potential of bacteriocins to combat SARS-CoV-2 infection hasThese antimicrobial peptides have been suggested as effective antiviral therapeutics and therapeuticSpecific attention is given to the antiviral mechanisms of the molecules along with their integrative

Keywords： antimicrobial proteins / antiviral profiling of bacteriocins / antiviral therapeutics / immunomodulation

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IN VITRO ACTIVITY OF EXTRACTS OF FIVE MEDICINAL PLANT SPECIES ON PLANT PATHOGENIC FUNGI

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 4, Pages 635-644 doi: 10.15302/J-FASE -2020343

Abstract:

The antifungal effectiveness of extracts of five medicinal plant species was determined.chinensis and Pyrola calliantha were evaluated against the mycelial growth of the plantAll plant extracts were prepared at 60°C using solvents (either water, 50% ethanol (v/v),Different extracts from the same plant species gave different degrees of inhibition.

Keywords： Botrytis cinerea / food preservation / plant diseases / plant pathogenic fungi / Tupistra chinensis

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Current recommendations of managing HBV infection in preconception or pregnancy

James S. Park,Calvin Pan

Frontiers of Medicine 2014, Volume 8, Issue 2, Pages 158-165 doi: 10.1007/s11684-014-0340-4

Abstract: The emerging data suggest that initiation of antiviral therapy in the beginning of the third trimesterIn order to minimize the fetal exposure to the antiviral medication, antiviral therapy during the pregnancyand after the pregnancy; the risk factors that increase mother-to-child transmission; safety data on antiviral

Keywords： antiviral therapy Caesarean section cirrhosis hepatitis B immunoprophylaxis mother-to-child transmission

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Oral administration of

Sufen ZHAO,Yuanyuan JIA,Weiwei ZHANG,Lili WANG,Yunfei MA,Kedao TENG

Frontiers of Agricultural Science and Engineering 2015, Volume 2, Issue 4, Pages 318-326 doi: 10.15302/J-FASE-2015080

Abstract: Garlic ( Liliaceae) has been safely used for more than 5000 years, and research on garlic extract is rapidly increasing because of its multiple biological functions. The effects of oral administration of garlic mixture (GM, water-soluble extract) on infectious bursal disease virus (IBDV)-infected specific pathogen free male white leghorn chicken were examined through histopathological, immunohistochemical, and Western blot analyses, and enzyme-linked immunosorbent assay. The results confirmed the protective effects of oral administration of 5 mg·kg BW GM (Group GM1) on bursal lesions after IBDV infection. In particular, protein expression of IBDV in the bursa decreased in Group GM1, indicating that GM administration decreased IBDV replication in the bursa. Furthermore, immunoglobulin M- and A-bearing B lymphocytes significantly increased 7 days post infection in bursae in Group GM1 ( <0.01), suggesting that the oral administration of 5 mg·kg GM offers moderate protection against B cell destruction after IBDV infection. During infection, the concentration of bursal interferon gamma (IFN-g) increased and peaked in Group GM1 earlier than in Group T (IBDV-exposed), demonstrating that GM administration prompted the production of IFN-g to protect against IBDV infection.

Keywords： garlic infectious bursal disease virus (IBDV) antiviral effect IgM-bearing B lymphocyte

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ACTIVITY OF EXTRACTS OF FIVE MEDICINAL PLANT SPECIES ON PLANT PATHOGENIC FUNGI

Shufeng YAO, Jiali XU, Haibo ZHANG, Hong GAO, Shibin SHANG, Dan WANG

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 4, Pages 635-644 doi: 10.15302/J-FASE-2020343

Abstract: The antifungal effectiveness of extracts of five medicinal plant species was determined.inhibitory activity of extracts of , , , and were evaluated against the mycelial growth of the plantAll plant extracts were prepared at 60°C using solvents (either water, 50% ethanol ( ), 95% ethanol (Different extracts from the same plant species gave different degrees of inhibition.

Keywords： Botrytis cinerea food preservation plant diseases plant pathogenic fungi Tupistra chinensis

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A brief review of microRNA and its role in PRRSV infection and replication

Xuekun GUO,Wenhai FENG

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 2, Pages 114-120 doi: 10.15302/J-FASE-2014022

Abstract: replication by multiple ways such as targeting viral genomic RNA, targeting viral receptor and inducing antiviral

Keywords： porcine reproductive and respiratory syndrome virus (PRRSV) microRNA antiviral viral tropism

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An introduction to the medicinal plant genome project

Shilin Chen, Li Xiang, Xu Guo, Qiushi Li

Frontiers of Medicine 2011, Volume 5, Issue 2, Pages 178-184 doi: 10.1007/s11684-011-0131-0

Abstract: In recent years, genomics has developed rapidly with the application of next-generation sequencing technology. However, very few studies have been carried out on genomics for medicinal plants. This paper introduces the genome research of medicinal plants, including genome sequencing, assembly, annotation, and functional genomics, to set up the foundation for the development of natural medicines and the selection of cultivars with good agricultural traits. This study places the study on traditional Chinese medicine into the frontier field of life science.

Keywords： genomics medicinal plant sequencing application

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HEMIPTERAN-TRANSMITTED PLANT VIRUSES: RESEARCH PROGRESS AND CONTROL STRATEGIES

Frontiers of Agricultural Science and Engineering 2022, Volume 9, Issue 1, Pages 98-109 doi: 10.15302/J-FASE-2021389

Abstract:

About 80% of plant viruses are transmitted by specific insect vectors, especially hemipterans withThis review summarizes the latest research findings on the interactions between plant viruses and insectvectors and analyzes the key factors affecting insect transmission of plant viruses from the perspectivestransmission of animal viruses, potential control strategies to prevent the transmission of insect-vectored plant

Keywords： control strategies / feeding / immunity / insect vector / microorganism / plant virus

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Intelligent diagnosis methods for plant machinery

Huaqing WANG, Peng CHEN, Shuming WANG,

Frontiers of Mechanical Engineering 2010, Volume 5, Issue 1, Pages 118-124 doi: 10.1007/s11465-009-0084-z

Abstract: several intelligent diagnostic approaches based on artificial neural network and fuzzy algorithm for plantdiagnostic methods have been successfully applied to condition diagnosis in different types of practical plant

Keywords： intelligent diagnosis neural network fuzzy algorithm adaptive filtering plant machinery